Antiphospholipid Antibody Profile Stability Over Time: Prospective Results From the APS ACTION Clinical Database and Repository.
Elena GkrouzmanEcem SevimJackie FinikDanieli Castro de Oliveira AndradeVittorio PengoSavinio SciasciaMaria G G TektonidouAmaia UgarteCecilia Beatrice ChighizolaH Michael BelmontRosario Lopez-PedreraLanlan JiPaul R FortinMaria EfthymiouGuilherme Ribeiro Ramires de JésusD Ware BranchCecilia NalliMichelle A PetriEsther RodriguezRicard CerveraChristian LoodTatsuya AtsumiRohan WillisMaria Laura BertolacciniHannah CohenJacob RandDoruk Erkannull nullPublished in: The Journal of rheumatology (2020)
Approximately 80% of our international cohort patients with clinically meaningful aPL profiles at baseline remain stable at a median follow-up of 5 years; triple aPL-positivity increase the odds of a stable aPL profile. These results will guide future validation studies of stored blood samples through APS ACTION Core Laboratories.