The potential predictive value of tumor budding for neoadjuvant chemoradiotherapy response in locally advanced rectal cancer.
Tarkan JägerDaniel NeureiterMohammad FallahaPhilipp SchredlTobias KiesslichRomana UrbasEckhard KlieserJosef HolzingerFelix SedlmayerKlaus EmmanuelAdam DinnewitzerPublished in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2018)
Our data confirm tumor budding as a strong prognostic factor and its potential predictive value for neoadjuvant chemoradiotherapy response in locally advanced rectal cancer patients. This provides the opportunity to modify and individualize neoadjuvant therapy regimens for non-responders.