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Integrated network pharmacology and GC-MS-based metabolomics to investigate the chemical profile and efficacy of Anemarrhenae Rhizoma and its processed products.

Wenyu LiJinhuan WeiXi TianHuiyi ZhangMengxin YangYukun NiuQian ZhangNan WangYiran JinYingfeng Du
Published in: Rapid communications in mass spectrometry : RCM (2024)
The method developed provides a novel strategy for the identification of pharmacophores in AR and SAR, as well as establishing a foundation for the exploration of the volatile differential components and pharmacodynamics in various processed products of TCMs. Additionally, the findings of this study can serve as a theoretical framework for the development and utilization of volatile components in AR and its processed derivatives.
Keyphrases
  • gas chromatography
  • mass spectrometry
  • high resolution