Analytical validation of an ELISA for the measurement of feline pancreas-specific lipase and re-evaluation of the reference interval and decision threshold for diagnosing pancreatitis.

Yu-An WuJörg M SteinerElke HuisingaMelissa J BeallJesse BuchGeoffrey T FosgateJonathan A Lidbury

Published in: Veterinary clinical pathology (2023)

The Spec fPL assay is analytically valid, and results suggest that a decision threshold of 8.8 μg/L would have high diagnostic specificity for excluding clinically healthy cats.

Keyphrases

decision making
high throughput
liquid chromatography
monoclonal antibody
mass spectrometry
structural basis