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Deciphering the distinct transcriptomic and gene regulatory map in adult macaque basal ganglia cells.

Zihao LiYunong SunLingjun DingJing YangJinrong HuangMengnan ChengLiang WuZhenkun ZhuangCheng ChenYunqi HuangZhiyong ZhuSiyuan JiangFubaoqian HuangChunqing WangShiping LiuLongqi LiuYing Lei
Published in: GigaScience (2023)
In general, our macaque basal ganglia atlas provides valuable insights into the comprehensive transcriptome and epigenome of the most important and populous cell populations in the macaque basal ganglia. We have identified 49 cell types based on transcriptomic profiles and 47 cell types based on epigenomic profiles, some of which exhibit region specificity, and characterized the molecular relationships underlying these brain regions.
Keyphrases
  • single cell
  • rna seq
  • cell therapy
  • induced apoptosis
  • gene expression
  • stem cells
  • genome wide
  • bone marrow
  • single molecule
  • cerebral ischemia