Precursor B-ALL Cell Lines Differentially Respond to SYK Inhibition by Entospletinib.

Sina SenderAnett SekoraSimon Villa PerezOleksandra ChabanovskaAnnegret BeckerAnaclet NgezahayoChristian JunghanssHugo Murua Escobar

Published in: International journal of molecular sciences (2021)

Different acting modes of Ento, independent of pre-BCR dependency, were characterized, unexpected in SEM. Accordingly, SYK classifies as a potential target structure in a subset of pro-B-ALLs.

Keyphrases

tyrosine kinase
acute lymphoblastic leukemia
anti inflammatory
human health
climate change