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Tanshinone IIA Inhibits Osteosarcoma Growth through a Src Kinase-Dependent Mechanism.

Chao HuXiaobin ZhuTaogen ZhangZhouming DengYuanlong XieFeifei YanLin Cai
Published in: Evidence-based complementary and alternative medicine : eCAM (2021)
Tanshinone IIA plays an antiosteosarcoma role in vitro and in vivo and inhibits the progression of osteosarcoma mediated by Src downstream of the MAPK/ERK and PI3K/AKt signaling pathways.
Keyphrases
  • pi k akt
  • signaling pathway
  • tyrosine kinase
  • cell cycle arrest
  • cell proliferation
  • induced apoptosis
  • epithelial mesenchymal transition
  • oxidative stress