Comprehensive preimplantation genetic testing for balanced insertional translocation carriers.
Shuo ZhangZhenle PeiMin XiaoJing ZhouBin HuSaijuan ZhuXiaoxi SunJunping WuCaixia LeiCongjian XuPublished in: Journal of medical genetics (2024)
The proposed method facilitates comprehensive chromosome screening and the concurrent identification of balanced insertions or normal karyotypes in embryos. This study offers an effective and universally applicable strategy for BIT carriers to achieve a healthy pregnancy and prevent the transmission of BITs to their offspring.