Drastic promotion of guanine oxidation via electron transfer in Ψ-type DNA.

Shunsuke SakuraiMayu EsumiMakiko Tanaka

Published in: Chemical communications (Cambridge, England) (2019)

We investigated the effects of a crowded environment on guanine oxidation in pyrene-modified oligonucleotides by photoinduced electron transfer. We observed drastic promotion of guanine oxidation in Ψ (psi; polymer- and salt-induced)-type DNA.

Keyphrases

electron transfer
circulating tumor
cell free
single molecule
nucleic acid
high glucose
diabetic rats
drug induced
atomic force microscopy
endothelial cells
mass spectrometry
high resolution
circulating tumor cells