Bacterial pathogens in peritoneal dialysis peritonitis: Insights from next-generation sequencing.

Wesley G van Hougenhouck-TullekenPedro H LebreMohamed SaidDon A Cowan

Published in: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis (2020)

For the clinician, our results suggest that PD peritonitis may often be a polymicrobial disease and that treating a dominant organism may not totally eradicate all bacterial contamination within the peritoneum. For the clinical scientist, additional use of a larger 16S rRNA segment (V5 or V6) is likely to outperform the use of the V4 segment only.

Keyphrases

peritoneal dialysis
end stage renal disease
chronic kidney disease
risk assessment
drinking water
copy number
gram negative
gene expression
human health
dna methylation
climate change
heavy metals
multidrug resistant