A Xanthan-Gum-Stabilized PEG-Conjugated Nanocurcumin Complex: Telescoping Synthesis for Enhanced Permeation Potential.

Prem Pandey Supriya Chaturvedi Rutuja Gumathannavar Mandar M ShirolkarVijay KanuruAtul Kulkarni Sang Hyun Moh

Published in: ChemistryOpen (2023)

We report a facile room temperature telescoping synthesis of a nanocurcumin complex with 17.5-fold permeation enhancement as determined by comparative in vitro permeation study with raw curcumin. The permeation results were further validated with in silico drug absorption prediction using ADMET predictors.

Keyphrases

room temperature
molecular docking
photodynamic therapy
quantum dots
emergency department
gold nanoparticles
human health
highly efficient
climate change