Claudin-6 is a single prognostic marker and functions as a tumor-promoting gene in a subgroup of intestinal type gastric cancer.

Tomohiro KohmotoKiyoshi MasudaKatsutoshi ShodaRizu TakahashiSae UjiroShoichiro TangeDaisuke IchikawaEigo OtsujiIssei Imoto

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2019)

This study identified CLDN6 as a GC-promoting gene, suggesting that CLDN6 to be a possible single prognostic marker and promising therapeutic target for a subset of GC patients.

Keyphrases

end stage renal disease
ejection fraction
genome wide
copy number
chronic kidney disease
prognostic factors
genome wide identification
patient reported outcomes
gas chromatography
transcription factor
study protocol
simultaneous determination