Small extracellular vesicles facilitate epithelial-mesenchymal transition in chronic rhinosinusitis with nasal polyps via the miR-375-3p/QKI axis.
X WangR ZhengW LiangH QiuT YuanW WangH DengW KongJ ChenY BaiY LiY ChenQ WuS WuX HuangZ ShiQ FuY ZhangQ Yang
Published in: Rhinology (2024)
MiR-375-3p-enriched sEVs facilitated EMT by suppressing QKI in hNECs. The association of miR-375-3p with disease severity underscores its potential as both a diagnostic marker and a therapeutic target for the innovative management of CRSwNP.