Lifestyle Affects Amyloid Burden and Cognition Differently in Men and Women.

Dario BachmannZachary J RomanAndreas BuchmannIsabelle ZuberSandro StuderAntje SaakeKatrin RauenEsmeralda GruberRoger M NitschChristoph HockAnton F Gietl Valerie Treyer

Published in: Annals of neurology (2022)

Sex modifies effects of certain lifestyle-related factors on amyloid burden and cognition. Notably, our results suggest that the negative impact of metabolic/vascular risk influences the risk of cognitive decline and Alzheimer's disease through distinct paths in women and men. ANN NEUROL 2022;92:451-463.

Keyphrases

cognitive decline
mild cognitive impairment
metabolic syndrome
weight loss
physical activity
cardiovascular disease
polycystic ovary syndrome
white matter
risk factors
middle aged
breast cancer risk
pregnancy outcomes
type diabetes
neural network
adipose tissue