Electrical impedance myography for assessment of Duchenne muscular dystrophy.
Seward B RutkoveKush KapurCraig M ZaidmanJim S WuAmy PasternakLavanya MadabusiSung YimAdam PacheckHeather SzelagTim HarringtonBasil T DarrasPublished in: Annals of neurology (2017)
EIM detects deterioration in muscles of both younger and older boys by 6 months; it also identifies the therapeutic effect of corticosteroid initiation. Because EIM is rapid to apply, painless, and requires minimal operator training, the technique deserves to be further evaluated as a biomarker in DMD clinical therapeutic trials. Ann Neurol 2017;81:622-632.