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An institutional experience: A retrospective analysis of the effect of transitioning from follicular lesion of undetermined significance to atypia of undetermined significance with subclassified atypia on interobserver concordance, rates of neoplasia, and rates of malignancy.

Lauren Kroll-WheelerRichard L CantleyJudy C PangBrian S SolesBrian SmolaXin JingMadelyn Lew
Published in: Diagnostic cytopathology (2020)
RON for AUS predominantly Hürthle cells subcategory was higher than previously reported, which may indicate use for tailored patient management pathways. AUS subclassification can result in significant interobserver variability. Therefore, institutions may consider consensus/quality control sessions to optimize diagnostic concordance.
Keyphrases
  • quality control
  • induced apoptosis
  • cell cycle arrest
  • case report
  • high grade
  • endoplasmic reticulum stress
  • clinical practice
  • cell death
  • cell proliferation
  • african american