A new physiological medium uncovers biochemical and cellular alterations in Lesch-Nyhan disease fibroblasts.

Paula Escudero-FerruzNeus OntiverosClaudia Cano-EstradaDiane J SutcliffeH A JinnahRosa J TorresJosé M López

Published in: Molecular medicine (Cambridge, Mass.) (2024)

A complete physiological cell culture medium reveals new alterations in Lesch-Nyhan disease. This work emphasizes the importance of using physiological cell culture conditions when studying a metabolic disorder.

Keyphrases

extracellular matrix