Right atrial function is associated with RV diastolic stiffness: RA-RV interaction in pulmonary arterial hypertension.
Jeroen N WesselsSophia-Anastasia MouratoglouJessie van WezenbeekM Louis HandokoJ Tim MarcusLilian J MeijboomBerend E WesterhofHarm Jan BogaardGustav J StrijkersAnton Vonk NoordegraafFrances S de ManPublished in: The European respiratory journal (2021)
In PAH, RA function is associated with changes in RV function. Despite increased RA stroke work, severe RV diastolic stiffness is associated with reduced RV active filling and increased vena cava backflow. In 50% of high baseline Eed patients, diastolic stiffness remains high, despite treatment. Eed reduction coincided with a large reduction in afterload, increased RV active filling and decreased vena cava backflow.
Keyphrases
- mycobacterium tuberculosis
- vena cava
- pulmonary arterial hypertension
- ejection fraction
- left ventricular
- blood pressure
- rheumatoid arthritis
- inferior vena cava
- end stage renal disease
- atrial fibrillation
- pulmonary hypertension
- newly diagnosed
- ankylosing spondylitis
- disease activity
- peritoneal dialysis
- heart failure
- prognostic factors
- early onset
- pulmonary embolism
- patient reported outcomes
- polycyclic aromatic hydrocarbons
- mitral valve
- replacement therapy
- idiopathic pulmonary fibrosis
- brain injury