Local delivery of tacrolimus using electrospun poly-ε-caprolactone nanofibres suppresses the T-cell response to peripheral nerve allografts.
Victoria H RobertonHolly N GregoryUkrit AngkawinitwongOmar MokraneAshleigh S BoydRebecca J ShipleyGareth R WilliamJames B PhillipsPublished in: Journal of neural engineering (2022)
These findings demonstrate proof of concept for a novel nanofibrous biomaterial-based targeted drug delivery strategy for immunosuppression in peripheral nerve allografting.