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Optimal Donor Selection for Hematopoietic Cell Transplantation Using Bayesian Machine Learning.

Brent R LoganMartin J MaiersRodney A SparapaniPurushottam W LaudStephen R SpellmanRobert E McCullochBronwen E Shaw
Published in: JCO clinical cancer informatics (2021)
We confirmed the singular importance of selecting the youngest available MUD, irrespective of patient features, identified potential for improved HCT outcomes by selecting a younger MUD, and demonstrated use of novel ML models transferable to optimize other complex treatment decisions in a patient-specific way.
Keyphrases
  • machine learning
  • artificial intelligence
  • big data
  • type diabetes
  • combination therapy
  • climate change
  • cell cycle arrest
  • skeletal muscle
  • adipose tissue