Optimal Donor Selection for Hematopoietic Cell Transplantation Using Bayesian Machine Learning.
Brent R LoganMartin J MaiersRodney A SparapaniPurushottam W LaudStephen R SpellmanRobert E McCullochBronwen E ShawPublished in: JCO clinical cancer informatics (2021)
We confirmed the singular importance of selecting the youngest available MUD, irrespective of patient features, identified potential for improved HCT outcomes by selecting a younger MUD, and demonstrated use of novel ML models transferable to optimize other complex treatment decisions in a patient-specific way.