Polygenic risk scores and the prediction of onset of mood and psychotic disorders in adolescents and young adults.
Jan ScottJacob J CrouseSarah MedlandEnda ByrneFrank IorfinoBrittany MitchellNathan A GillespieNicholas MartinNaomi WrayIan B HickiePublished in: Early intervention in psychiatry (2023)
The findings need replication. However, this exploratory study suggests that combining PRS with other risk factors has the potential to improve outcome prediction in youth.