Sensitivity-Specificity of Tau and Amyloid β Positron Emission Tomography in Frontotemporal Lobar Degeneration.
Alma GhirelliNirubol TosakulwongStephen D WeigandHeather M ClarkFarwa AliHugo BothaJoseph R DuffyRene L UtianskiMarina BuciucMelissa E MurraySydney A LabuzanAnthony J SpychallaNha Trang Thu PhamChristopher G SchwarzMatthew L SenjemMary M MachuldaMatthew BakerRosa RademakersMassimo FilippiClifford R JackVal J LoweJoseph E ParisiGourisankar GhoshKeith Anthony JosephsJennifer L WhitwellPublished in: Annals of neurology (2020)
Molecular PET shows expected correlations with Alzheimer-related pathology but lacks sensitivity to detect mild Alzheimer pathology in FTLD. Regional flortaucipir uptake was able to separate CBD and PSP. ANN NEUROL 2020;88:1009-1022.