Evaluating the safety and efficacy of daprodustat for anemia of chronic kidney disease: a meta-analysis of randomized clinical trials.
Kaneez FatimaWarda AhmedAsad Saulat FatimiOmar MahmudMuhammad Umar MaharAyesha AliSyed Roohan AamirMuhammad Taha NasimMuhammad Bilal IslamMuhammad Talha ManiyaDua AzimShayan MarsiaTalal AlmasPublished in: European journal of clinical pharmacology (2022)
Daprodustat has similar efficacy compared to rhEPO for the treatment of anemia of CKD. On treatment, the reduced experience of MACE was reported in DD-CKD patients as compared to rhEPO. Furthermore, effects on iron metabolism varied by parameter, with daprodustat being superior to rhEPO in some cases and inferior in others.