Application of cell-free DNA fungal polymerase chain reaction for invasive fungal disease evaluation in pediatric oncology and stem cell transplant patients.

Lauren E KushnerHayden T SchwenkFeiFei QinDerek BoothroydCatherine Aftandilian

Published in: Pediatric blood & cancer (2024)

Plasma cfDNA fungal PCRs detected relevant molds or yeast in most cases classified as proven/probable IFD. However, this targeted approach missed some cases. More studies are required to determine optimal utilization of molecular diagnostics in pediatric patients.

Keyphrases

stem cells
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
palliative care
prognostic factors
peritoneal dialysis
drug delivery
young adults
childhood cancer