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A [3]Rotaxane Host Selects Between Stereoisomers.

Mathieu DenisStephen Michael Goldup
Published in: Angewandte Chemie (International ed. in English) (2018)
What has it got in its pockets? A new approach to the selective binding and reporting of stereoisomers using mechanical bonding to produce a well-defined three-dimensional binding pocket was recently reported by Beer and co-workers. The highly stereoselective binding of stereoisomers by the reported [3]rotaxane suggest that the use of the mechanical bond to engineer a binding pocket has great potential for the development of stereoselective hosts.
Keyphrases
  • dna binding
  • binding protein
  • transcription factor
  • risk assessment
  • climate change