LC-HRMS and GC-MS Profiling of Urine Free Cortisol, Cortisone, 6Β-, and 18-Hydroxycortisol for the Evaluation of Glucocorticoid and Mineralocorticoid Disorders.

Gregori CasalsMaría Antonieta BallesterosAngielys ZamoraIrene MartínezGuillermo Fernández-VaroMireia MoraFelicia A HanzuManuel Morales-Ruiz

Published in: Biomolecules (2024)

A rapid and accurate routine LC-HRMS method was validated, which is useful for the evaluation of hypercortisolism and other disorders of glucocorticoid and mineralocorticoid metabolism.

Keyphrases

high resolution mass spectrometry
liquid chromatography
simultaneous determination
mass spectrometry
high resolution
clinical practice
single cell
sensitive detection