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Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy.

Jiayue QiuXiangmei LiYalan HeQian WangJi LiJiashuo WuYing JiangJunwei Han
Published in: Journal of translational medicine (2022)
was demonstrated to be an effective predictor of immunotherapeutic benefit in seven independent immunotherapy cohorts and may serve as a potential and convenient biomarker for the clinical application of ICB therapy.
Keyphrases
  • signaling pathway
  • pi k akt
  • epithelial mesenchymal transition
  • stem cells
  • bioinformatics analysis
  • oxidative stress
  • bone marrow
  • climate change
  • smoking cessation