Neighbor cells restrain furrowing during epithelial cytokinesis.
Jennifer LandinoEileen MisterovichShahana A ChumkiAnn L MillerPublished in: bioRxiv : the preprint server for biology (2023)
Neighboring cells assemble actomyosin arrays adjacent to the cytokinetic furrowOverexpression of an F-actin cross-linker in neighbor cells slows furrowingOptogenetic activation of contractility in one neighbor pauses furrow ingressionHyper-contractility in both neighbors restrains furrowing & cells fail cytokinesis.