Relationships of maternal body mass index and plasma biomarkers with childhood body mass index and adiposity at 6 years: The Children of SCOPE study.

Kathryn V Dalrymple John M D Thompson Shahina Begum Keith M Godfrey Lucilla PostonPaul T SeedLesley M E McCowan Clare Rosemary Wall Andrew N ShellingRobyn NorthWayne S Cutfield Edwin A Mitchellnull null

Published in: Pediatric obesity (2019)

In this contemporary large prospective cohort study with extensive maternal/childhood phenotyping and a high prevalence of maternal overweight/obesity, we found independent relationships of maternal early pregnancy BMI with childhood BMI and adiposity; similar associations were observed with PlGF, which may imply a role for placenta function in the developmental programming of childhood obesity risk.

Keyphrases

weight gain
birth weight
body mass index
insulin resistance
pregnancy outcomes
weight loss
early life
type diabetes
metabolic syndrome
physical activity
high throughput
childhood cancer
gestational age
high fat diet induced