FARP-1 deletion is associated with lack of response to autism treatment by early start denver model in a multiplex family.

Francesca CucinottaArianna RicciardelloLaura TurrizianiGiorgia CalabreseMarilena BriguglioMaria BoncoddoFabiana BellomoPasquale TomaiuoloSilvia MartinesMarianna BruschettaFrancesca La Fauci BelponerTiziana Di BellaCostanza ColombiMarco BaccarinChiara PicinelliPaola CastronovoCarla LintasRoberto SaccoThomas BiedererBarbara KellamStephen W SchererAntonio M Persico

Published in: Molecular genetics & genomic medicine (2020)

These results represent a paradigmatic example of the heuristic potential of genetic markers in predicting treatment response and possibly in supporting the targeted prescription of specific early intervention approaches.

Keyphrases

autism spectrum disorder
high throughput
genome wide
cancer therapy
copy number
combination therapy
replacement therapy
single cell