lncRNA JPX Promotes Tumor Progression by Interacting with and Destabilizing YTHDF2 in Cutaneous Melanoma.

Dan Luo Hui Tang Liuchang Tan Long Zhang Lei Wang Qionghui Cheng Xia Lei Jinjin Wu

Published in: Molecular cancer research : MCR (2024)

This study highlights the ubiquitination effect of USP10 and JPX on YTHDF2 in cutaneous melanoma, and proposes that the JPX/USP10/YTHDF2/BMP2 axis may be a prospective therapeutic target for cutaneous melanoma.

Keyphrases

skin cancer
mesenchymal stem cells
long non coding rna
protein kinase