Substrate recognition principles for the PP2A-B55 protein phosphatase.

Thomas KruseDimitriya H GarvanskaJulia VargaWilliam GarlandBrennan McEwanJamin B HeinMelanie Bianca WeisserIker Benavides PuyCamilla Bachman ChanPaula Sotelo ParrilaBlanca Lopez MendezJeyaprakash ArulanandamOra Schueler-FurmanTorben Heick JensenArminja KettenbachJakob Nilsson

Published in: bioRxiv : the preprint server for biology (2024)

α-helices in PP2A-B55 substrates bind a conserved pocket on B55 through a common mechanism that is conserved in eukaryotes.

Keyphrases

transcription factor
amino acid
protein protein
protein kinase
small molecule