HIV-1 Drug Resistance Detected by Next-Generation Sequencing among ART-Naïve Individuals: A Systematic Review and Meta-Analysis.

Fei OuyangDefu YuanWenjing ZhaiShanshan LiuYing ZhouHaitao Yang

Published in: Viruses (2024)

In this study, we found that next-generation sequencing facilitates a more sensitive detection of HIV-1 drug resistance than SGS. The high prevalence of PDR emphasizes the importance of baseline resistance and assessing the threshold for optimal clinical detection using NGS.

Keyphrases

antiretroviral therapy
sensitive detection
hiv infected
hiv positive
loop mediated isothermal amplification
hiv testing
human immunodeficiency virus
hiv aids
hepatitis c virus
men who have sex with men
copy number
quantum dots
circulating tumor
gene expression
dna methylation
circulating tumor cells