Subthalamic stimulation has acute psychotropic effects and improves neuropsychiatric fluctuations in Parkinson's disease.
Andreia D MagalhãesDeborah AmstutzKatrin PetermannInes DeboveMário SousaMarie E Maradan-GachetMartin Lenard LachenmayerJulia WaskönigSandra Murcia-CarreteroAndreas Antonios DiamantarasGerd TinkhauserAndreas NowackiClaudio PolloCarmen Rodriguez-BlazquezPablo Martinez-MartinPaul KrackPublished in: BMJ neurology open (2024)
Bilateral STN-DBS at therapeutic parameters has acute psychotropic effects similar to levodopa and can modulate and decrease levodopa-induced neuropsychiatric fluctuations.