Multiple system atrophy in Hokkaido, Japan: a prospective registry study of natural history and symptom assessment scales followed for 5 years.
Masaaki MatsushimaIchiro YabeKen SakushimaYasuhiro KanataniNaoki NishimotoTakeshi MatsuokaJun SawadaHaruo UesugiKazuya SakoAsako TakeiAkiko TamakoshiShun ShimohamaNorihiro SatoSeiji KikuchiHidenao SasakiPublished in: BMJ open (2021)
This study is the first large-scale prospective MSA cohort study in Asia. MSA-C was dominant, but the use of antiparkinsonian drugs increased over the study period. Changes from MSA-C to MSA-P occurred, but not vice versa.
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