Repurposing a fracture risk calculator (FRAX) as a screening tool for women at risk for sarcopenia.

Julie A Pasco Mohammadreza Mohebbi Monica C Tembo Kara L Holloway-Kew Natalie K Hyde Lana J Williams Mark A Kotowicz

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2020)

Here we provide preliminary evidence to suggest that FRAX probabilities without BMD might predict sarcopenia with high sensitivity and reasonable specificity. Given that FRAX clinical risk factors are identified without equipment, there is potential to use this or a modified version of the FRAX tool to screen for individuals at risk of sarcopenia.

Keyphrases

skeletal muscle
risk factors
community dwelling
polycystic ovary syndrome
high throughput
psychometric properties
risk assessment
single cell
climate change
hip fracture
structural basis