A bitter flavonoid gum from Dorema aucheri accelerate wound healing in rats: Involvement of Bax/HSP 70 and hydroxyprolin mechanisms.

Khaled Abdul-Aziz AhmedAhmed A J JabbarMohammed M Hussein M RaoufAyman M Al-QaanehRamzi A MothanaAbdullah R AlanziFuad Othman AbdullahRawaz Rizgar HassanMahmood Ameen AbdullaMusher Ismael SalehSidgi Hasson

Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)

The present wound contraction by DAG might be linked with the modulatory effect of its phytochemicals (polysaccharides, flavonoids, and phenolic) on the cellular mechanisms, which justify their folkloric use and provokes further investigation as therapeutic drug additives for wound contraction.

Keyphrases

wound healing
smooth muscle
heat shock protein
surgical site infection
heat stress
heat shock
emergency department
drug induced