Kappa free light chains in cerebrospinal fluid to identify patients with oligoclonal bands.

Marie SüßeM HannichA PetersmannS ZyllaM PietznerM NauckA Dressel

Published in: European journal of neurology (2018)

The KFLC index with a cut-off value of 3.61 had high diagnostic accuracy to predict immunoglobulin G synthesis via OCB analysis. Determination of the KFLC index provided a quantitative parameter that could be used as an initial diagnostic step in inflammatory central nervous system disorders before measuring OCB.

Keyphrases

cerebrospinal fluid
nuclear factor
oxidative stress
high resolution
molecularly imprinted
toll like receptor
mass spectrometry
inflammatory response