Characterization of cellular senescence in radiation ulcers and therapeutic effects of mesenchymal stem cell-derived conditioned medium.

Wanchao ChenYang WangJiancheng ZhengYan ChenCan ZhangWei YangLingling WuZeyu YangYu WangChunmeng Shi

Published in: Burns & trauma (2023)

Our findings not only characterize the roles of cellular senescence in the progression of radiation ulcers but also indicate the therapeutic potential of senescent cells in their treatment.

Keyphrases

induced apoptosis
dna damage
mesenchymal stem cells
endothelial cells
cell cycle arrest
stress induced
bone marrow
radiation induced
wound healing
endoplasmic reticulum stress
oxidative stress
combination therapy
radiation therapy
cell proliferation