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Persistent reduction of mucosal-associated invariant T cells in primary biliary cholangitis.

Toru SetsuSatoshi YamagiwaKentaro TominagaNaruhiro KimuraHiroki HondaHiroteru KamimuraAtsunori TsuchiyaMasaaki TakamuraShuji Terai
Published in: Journal of gastroenterology and hepatology (2018)
These findings suggested that MAIT cells were activated, exhausted, and persistently depleted in PBC patients even after ursodeoxycholic acid treatment, possibly as a consequence of persistent liver inflammation.
Keyphrases
  • end stage renal disease
  • induced apoptosis
  • ejection fraction
  • newly diagnosed
  • oxidative stress
  • chronic kidney disease
  • prognostic factors
  • cell cycle arrest
  • cell death
  • endoplasmic reticulum stress