Persistent reduction of mucosal-associated invariant T cells in primary biliary cholangitis.
Toru SetsuSatoshi YamagiwaKentaro TominagaNaruhiro KimuraHiroki HondaHiroteru KamimuraAtsunori TsuchiyaMasaaki TakamuraShuji TeraiPublished in: Journal of gastroenterology and hepatology (2018)
These findings suggested that MAIT cells were activated, exhausted, and persistently depleted in PBC patients even after ursodeoxycholic acid treatment, possibly as a consequence of persistent liver inflammation.