Involvement of SIRT3-GSK3β deacetylation pathway in the effects of maternal diabetes on oocyte meiosis.

Yongan XinYifei JinJuan GeZhenyue HuangLongsen HanCongyang LiDanni WangShuai ZhuQiang Wang

Published in: Cell proliferation (2020)

Our data identify GSK3β as a cytoskeletal regulator that is required for the assembly of meiotic apparatus, and discover a beneficial effect of SIRT3-dependent GSK3β deacetylation on oocyte quality from diabetic mice.

Keyphrases

pi k akt
signaling pathway
oxidative stress
type diabetes
cardiovascular disease
ischemia reperfusion injury
electronic health record
transcription factor
big data
cell proliferation
birth weight
pregnant women
quality improvement
metabolic syndrome
weight gain