Venous thromboembolism in a large cohort of children with acute lymphoblastic leukemia: Risk factors and effect on prognosis.

Irene L M KlaassenMandy N LauwMarta FioccoInge M van der SluisRob PietersSaskia MiddeldorpMarianne D van de WeteringHester A de Groot-KrusemanC Heleen van Ommen

Published in: Research and practice in thrombosis and haemostasis (2019)

Within this large pediatric ALL cohort, we demonstrated a high morbidity in CVST patients. Age ≥7 years at diagnosis and T-ALL subtype were the main risk factors for VTE, and should be considered in preventive strategies.

Keyphrases

venous thromboembolism
acute lymphoblastic leukemia
risk factors
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
direct oral anticoagulants
young adults
prognostic factors
allogeneic hematopoietic stem cell transplantation
patient reported