Lifetime exposure to smoking, epigenetic aging, and morbidity and mortality in older adults.

Eric T KlopackJudith E CarrollSteve W ColeTeresa E SeemanEileen M Crimmins

Published in: Clinical epigenetics (2022)

Results suggest epigenetic aging is one biological mechanism linking lifetime exposure to smoking with development of disease and earlier death in later life. Interventions aimed at reducing smoking in adulthood may be effective at weakening this association.

Keyphrases

smoking cessation
dna methylation
physical activity
gene expression
depressive symptoms