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Thyroid hormone levels in children with Prader-Willi Syndrome: A randomized controlled Growth Hormone (GH)-trial and 10-year GH study.

Demi J Trueba-TimmermansLionne N GrootjenGerthe F KerkhofEdmond H H M RingsAnita C S Hokken-Koelega
Published in: European journal of endocrinology (2024)
Our findings suggest that GH-treatment decreases FT4 levels, due to increased peripheral conversion of FT4 to T3 in the first months of treatment, but thereafter FT4 and T3 normalize and remain stable during long-term GH-treatment in almost all children and adolescents with PWS.
Keyphrases
  • growth hormone
  • clinical trial
  • case report