Genome-Wide Association Study Identifies Novel Colony Stimulating Factor 1 Locus Conferring Susceptibility to Cryptococcosis in Human Immunodeficiency Virus-Infected South Africans.

Shichina KannambathJoseph N JarvisRachel M WakeNicky LongleyAngela LoyseVicky MatzarakiRaúl Aguirre-GamboaCisca WijmengaRonan DoyleMaria PaximadisCaroline T TiemessenVinod KumarAlan PittmanGraeme MeintjesThomas S HarrisonMihai G NeteaTihana Bicanic

Published in: Open forum infectious diseases (2020)

This first genome-wide association study of susceptibility to cryptococcosis has identified novel and immunologically relevant susceptibility loci, which may help define novel strategies for prevention or immunotherapy of HIV-associated cryptococcal meningitis.

Keyphrases

genome wide association study
human immunodeficiency virus
antiretroviral therapy
hepatitis c virus
hiv infected
hiv positive
hiv aids
hiv testing
men who have sex with men
south africa
cerebrospinal fluid