Higher Mucosal Healing with Tumor Necrosis Factor Inhibitors in Combination with Thiopurines Compared to Methotrexate in Crohn's Disease.

Abhinav VasudevanAjay RaghunathShane AnthonyCian ScanlonMiles P SparrowPeter R GibsonDaniel R van Langenberg

Published in: Digestive diseases and sciences (2018)

In this cohort, anti-TNF and thiopurine co-therapy resulted in higher rates of mucosal healing than methotrexate, the difference is most pronounced with adalimumab and conversely with low-dose methotrexate.

Keyphrases

high dose
low dose
rheumatoid arthritis
ulcerative colitis
juvenile idiopathic arthritis
disease activity
bone marrow