Presentation and outcomes of Lassa fever in children in Nigeria: a prospective cohort study (LASCOPE).
Alexandre DuvignaudIjeoma C EtafoMarie JaspardQasim SalauBéatrice SerraAbiodun J KareemSylvain JuchetTolulope O JegedeDelphine GabillardAbiodun T AbidoyeCamille Le GalChukwuyem AbejegahSampson OwhinKevin OkwaraekeMahamadou DoutchiJackson Katembo VihundiraRene-M Besong-LacheBenjamin SeriMarion Bérerd-CamaraAlex P A SalamAdebola OlayinkaPeter HorbyEphraim Ogbaini-EmovonSophie DuraffourLiasu A AhmedStephan GüntherAkinola N AdedosuXavier AnglaretDenis MalvyHans J LangOladele O AyodejiPublished in: Journal of the Pediatric Infectious Diseases Society (2024)
The fatality rate for children over 12 months hospitalized with LF was lower than that previously reported for adults. Hypotension and acute kidney injury were the most frequent organ dysfunctions. Bleeding was relatively infrequent. Anemia and the need for transfusion were common, the relative contribution of ribavirin-induced hemolysis being unknown.