Nanoliposomal formulation of pistachio hull extract: preparation, characterization and anti-cancer evaluation through Bax/Bcl2 modulation.

Hamidreza HarandiSoudeh Khanamani Falahati-PourMehdi MahmoodiSanaz FaramarzHaniyeh MalekiFatemeh Bagheri NasabHamidreza ShiriSaba FooladiMohammad Hadi Nematollahi

Published in: Molecular biology reports (2022)

The flow cytometry and real-time PCR results indicated the potential of this liposomal extract as an anti-cancer drug candidate for the treatment of liver cancer in the future, and the mitochondrial pathway involving the up-regulation of the Bax/Bcl-2 ratio can mediate its impact.

Keyphrases

flow cytometry
real time pcr
oxidative stress
induced apoptosis
drug delivery
anti inflammatory
current status
emergency department
risk assessment
combination therapy
high resolution
mass spectrometry
drug induced
human health
clinical evaluation