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Study on the Anti-demyelination Mechanism of Bu-Shen-Yi-Sui Capsule in the Central Nervous System Based on Network Pharmacology and Experimental Verification.

Zheng ZhaYi-Jiang LiuSi-Si LiuNan ZhangJun-Ling LiFang QiLiang-Yun JinBing XueTao YangYong-Ping FanHui ZhaoLei Wang
Published in: Mediators of inflammation (2022)
-induced OLN-93 cell injury by increasing Akt phosphorylation to suppress oxidative stress and cell apoptosis. Therefore, BSYS can be potentially used for CNSD treatment. However, the results of this study are only derived from in vitro experiments, lacking the validation of in vivo animal models, which is a limitation of our study. We will further verify the underlying mechanisms of BSYS in animal experiments in the future.
Keyphrases
  • oxidative stress
  • signaling pathway
  • diabetic rats
  • dna damage
  • current status
  • high glucose
  • drug induced
  • stress induced