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Lessons learned and implications of early therapies for coronavirus disease in a territorial service centre in the Calabria region: a retrospective study.

Vincenzo ScaglioneSalvatore RotundoNadia MarascioCarmela De MarcoRosaria LionelloClaudia VenezianoLavinia BerardelliAngela QuirinoVincenzo OlivadeseFrancesca SerapideBruno TassoneHelen Linda MorroneChiara DavoliValentina La GambaAndrea BruniBruno Mario CesanaGiovanni MateraAlessandro RussoFrancesco Saverio CostanzoGiuseppe VigliettoEnrico Maria TrecarichiCarlo Tortinull null
Published in: BMC infectious diseases (2022)
A low rate of COVID-19 progression requiring hospital admission was observed in patients included in this study. The dedicated COVID-19 proximity territorial service appeared to strengthen the regional sanitary system, avoiding the overwhelming of other services. Importantly, our results also support early combination therapy: it is possible that this strategy reduces the emergence of escape mutants of SARS-CoV-2, thereby increasing efficacy of early treatment, especially in immunocompromised individuals.
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